Salmonella enterica Serotype Typhi with nonclassical quinolone resistance phenotype.

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Accou-Demartin, Marie | Gaborieau, Valérie | Song, Yajun | Roumagnac, Philippe | Marchou, Bruno | Achtman, Mark | Weill, François-Xavier

Edité par CCSD ; Centers for Disease Control and Prevention -

International audience. We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.

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