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Salmonella enterica Serotype Typhi with nonclassical quinolone resistance phenotype.
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Edité par CCSD ; Centers for Disease Control and Prevention -
International audience. We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.