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Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome

Archive ouverte | Maarouf, Adil | CCSD

International audience. Macrophages are important components of inflammatory processes in multiple sclerosis, closely linked to axonal loss, and can now be observed in vivo using ultra-small superparamagnetic iron o...

Ultra-small Super Paramagnetic Iron Oxide predicts higher disease activity in clinically isolated syndrome

Archive ouverte | Maarouf, Adil | CCSD

Background: Macrophages are important components of inflammatory processes inmultiple sclerosis, closely linked to axonal loss, and can now be observed in-vivo usingUltra-Small super-Paramagnetic Iron Oxide (USPIO). We aimed to de...

Results of a Phase 1b study to confirm safety and tolerability of olesoxime in multiple sclerosis patients

Archive ouverte | Pelletier, Jean | CCSD

International audience

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