Suggestions

Du même auteur

Neutral sphingomyelinase 2 heightens anti-melanoma immune response and synergizes with immune checkpoint inhibitors.

Archive ouverte | Montfort, Anne | CCSD

International audience. As part of a network of enzymes modulating the generation and degradation of sphingolipids, neutral sphingomyelinase 2 (nSMase2) catalyses the hydrolysis of the plasma membrane sphingomyelin ...

Targeting TNF alpha as a novel strategy to enhance CD8 + T cell-dependent immune response in melanoma?

Archive ouverte | Bertrand, Florie | CCSD

International audience. Tumor Necrosis Factor a (TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology, either acting as a cytotoxic effector produced by leukocytes or behaving as an immunosupp...

Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy

Archive ouverte | Montfort, Anne | CCSD

International audience. Dysregulation of lipid metabolism affects the behavior of cancer cells, but how this happens is not completely understood. Neutral sphingomyelinase 2 (nSMase2), encoded by SMPD3, catalyzes th...

Chargement des enrichissements...