CHK1 as a therapeutic target to bypass chemoresistance in AML

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David, Laure | Fernandez-Vidal, Anne | Bertoli, Sarah | Grgurevic, Srdana | Lepage, Benoît | Deshaies, Dominique | Prade, Naïs | Cartel, Maëlle | Larrue, Clément | Sarry, Jean-Emmanuel | Delabesse, Eric | Cazaux, Christophe | Didier, Christine | Récher, Christian | Manenti, Stéphane | Hoffmann, Jean-Sébastien

Edité par CCSD ; American Association for the Advancement of Science (AAAS) -

International audience. AML patients have new hope for overcoming resistance to therapy by inhibiting the DNA checkpoint kinase CHK1.

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