Continuous moderate and intermittent high-intensity exercise in youth with type 1 diabetes: Which protection for dysglycemia?

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Parent, Cassandra | Lespagnol, Elodie | Berthoin, Serge | Tagougui, Sémah | Stuckens, Chantal | Tonoli, Cajsa | Dupire, Michelle | Dewaele, Aline | Dereumetz, Julie | Dewast, Chloe | Gueorgieva, Iva | Rabasa-Lhoret, Remi | Heyman, Elsa

Edité par CCSD ; Elsevier -

International audience. From an early age, exercise is key to managing type 1 diabetes (T1D). However, hypoglycemia around aerobic exercise is a major barrier to physical activity in children. We explore whether intermittent high-intensity aerobic exercise (IHE), designed to mimic spontaneous childhood physical activity patterns, offers better protection against glycemic drop than continuous moderate-intensity exercise (CME). Five boys and 7 girls with T1D (9.8 ± 1.4y) performed ergo cycle-based randomized CME and IHE of identical duration and total mechanical load [50 %PWCvs. 15sec(150 %PWC)/30 sec passive recovery; both during two 10-min sets, 5 min in-between]. Capillary glycemia during exercise and interstitial glucose during recovery were compared between exercises and an inactive condition, controlling for baseline glycemia, carbohydrate and insulin. The exercise-induced decrease in capillary glycemia was attenuated by 1.47 mmol·L for IHE vs. CME (P  16.7 mmol·L compared with inactive days (P < 0.05; CME: 0 %; IHE: 16,7 %; INACTIVE: 41,7 %). IHE appeared to limit the glycemic drop compared to CME. Performing 20-min CME or IHE was not associated with increased hypoglycemic risk compared to being inactive. CME appeared even transiently protective against serious hyperglycemia.

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