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Cohesin complex oligomerization maintains end-tethering at DNA double-strand breaks

Archive ouverte | Phipps, Jamie | CCSD

Abstract DNA double-strand breaks (DSB) must be repaired to ensure genome stability. Crucially, DSB ends must be kept together for timely repair. In Saccharomyces cerevisiae , two poorly understood pathways mediate DSB end-tetheri...

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Archive ouverte | Forey, Romain | CCSD

International audience

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Archive ouverte | Penzo, Arianna | CCSD

International audience. Nuclear pore complexes (NPCs) have increasingly recognized interactions with the genome, as exemplified in yeast, where they bind transcribed or damaged chromatin. By combining genome-wide ap...

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