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Properties of rabies virus phosphoprotein and nucleoprotein biocondensates formed in vitro and in cellulo

Archive ouverte | Nevers, Quentin | CCSD

International audience. Rabies virus (RABV) transcription and replication take place within viral factories having liquid properties, called Negri bodies (NBs), that are formed by liquid-liquid phase separation (LLP...

Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates. La protéine P du virus de la rage se lie à TBK1 et interfère avec la formation de condensats liquides liés à l'immunité innée

Archive ouverte | Scrima, Nathalie | CCSD

International audience. Viruses must overcome the interferon-mediated antiviral response to replicate and propagate into their host. Rabies virus (RABV) phosphoprotein P is known to inhibit interferon induction. Her...

Biomolecular condensates with liquid properties formed during viral infections

Archive ouverte | Glon, Damien | CCSD

International audience. During a viral infection, several membraneless compartments with liquid properties are formed. They can be of viral origin concentrating viral proteins and nucleic acids, and harboring essent...

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