Biomolecular condensates with liquid properties formed during viral infections

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Glon, Damien | Léonardon, Benjamin | Guillemot, Ariane | Albertini, Aurélie | Lagaudrière-Gesbert, Cécile | Gaudin, Yves

Edité par CCSD ; Elsevier -

International audience. During a viral infection, several membraneless compartments with liquid properties are formed. They can be of viral origin concentrating viral proteins and nucleic acids, and harboring essential stages of the viral cycle, or of cellular origin containing components involved in innate immunity. This is a paradigm shift in our understanding of viral replication and the interaction between viruses and innate cellular immunity.

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