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Structure of the human TIP60-C histone exchange and acetyltransferase complex

Archive ouverte | Li, Changqing | CCSD

International audience. Chromatin structure is a key regulator of DNA transcription, replication and repair1. In humans, the TIP60–EP400 complex (TIP60-C) is a 20-subunit assembly that affects chromatin structure th...

Structure of SAGA and mechanism of TBP deposition on gene promoters

Archive ouverte | Papai, Gabor | CCSD

International audience. SAGA (Spt–Ada–Gcn5–acetyltransferase) is a 19-subunit complex that stimulates transcription via two chromatin-modifying enzymatic modules and by delivering the TATA box binding protein (TBP) ...

Molecular structure of promoter-bound yeast TFIID

Archive ouverte | Kolesnikova, Olga | CCSD

International audience. Transcription preinitiation complex assembly on the promoters of protein encoding genes is nucleated in vivo by TFIID composed of the TATA-box Binding Protein (TBP) and 13 TBPassociate factor...

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