Syracuse

Dynamique moléculaire de la transformation des progéniteurs myéloïdes. Molecular dynamics of myeloid progenitor transformation

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Arcangeli, Marie-Laure | Mazurier, Frédéric

Edité par CCSD ; John Libbey Eurotext -

International audience. Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults. AML results from the accumulation of abnormal immature myeloid progenitors, also called blasts, that are blocked in their differentiation. AML is a very heterogeneous disease with more than a dozen of genetically distinct entities (See new AML classification from [1]). Each genetically distinct AML subgroup is generally defined by gene mutations and/or alterations related to its aggressiveness, and is associated to [...]

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