In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4 + T H 1 cell response

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In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4 + T H 1 cell response

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Edité par CCSD ; American Association for the Advancement of Science (AAAS) -

International audience. Inactivation of SOCS1 optimizes adoptive T cell therapy including human CAR-T cell composition and efficacy.

Langue: en

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