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Archive ouverte | Sutra del Galy, Aurélien | CCSD

International audience. Inactivation of SOCS1 optimizes adoptive T cell therapy including human CAR-T cell composition and efficacy.

Optimized protocol to generate genome-wide inactivated Cas9-expressing murine T cells

Archive ouverte | Laprie-Sentenac, Marguerite | CCSD

International audience. In vivo genome-wide CRISPR screens in primary T cells allow the systematic and unbiased identification of non-redundant regulatory mechanisms shaping immune responses. Here, we present an opt...

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Archive ouverte | Bonnefond, Amélie | CCSD

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