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Of Dots and Stripes: The Morse Code of Micro-C Reveals the Ultrastructure of Transcriptional and Architectural Mammalian 3D Genome Organization
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Edité par CCSD ; Cell Press -
International audience. Using Micro-C, Hsieh et al. (2020) and Krietenstein et al. (2020) investigated 3D chromatin folding in human and mouse cells at unprecedented resolution, to uncover ultra-fine-scale chromatin structures that provide direct links between genome architecture, gene expression and gene regulation.