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Binding of Toxoplasma gondii glycosylphosphatidylinositols to galectin-3 is required for their recognition by macrophages

Archive ouverte | Debierre-Grockiego, Françoise | CCSD

International audience. We showed that the production of tumor necrosis factor (TNF) α by macrophages in response to Toxoplasma gondii glycosylphosphatidylinositols (GPIs) requires the expression of both Toll-like r...

Glycosylphosphatidylinositols of Toxoplasma gondii induce matrix metalloproteinase-9 production and degradation of galectin-3

Archive ouverte | Niehus, Sebastian | CCSD

International audience. Toxoplasma gondii glycosylphosphatidylinositols (GPIs) bind to galectin-3 to induce TNF-α production in macrophages via Toll-like receptors 2 and 4. Here we show that T. gondii GPIs stimulate...

Analysis of glycosylphosphatidylinositols of a virulent and a non virulent strain of Toxoplasma gondii. Possible role in parasite virulence

Archive ouverte | Niehus, Sebastian | CCSD

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