Afficher la couverture 'Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia. Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT | Neco, Patricia' en grand format
/5

0 avis

Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia. Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT

Archive ouverte

Neco, Patricia | Torrente, Angelo | Mesirca, Pietro | Zorio, Esther | Liu, Nian | Priori, Silvia, G. | Napolitano, Carlo | Richard, Sylvain | Benitah, Jean-Pierre | Mangoni, Matteo E. | Gómez, Ana Maria

Edité par CCSD ; American Heart Association -

International audience. Catecholaminergic polymorphic ventricular tachycardia is characterized by stress-triggered syncope and sudden death. Patients with catecholaminergic polymorphic ventricular tachycardia manifest sinoatrial node (SAN) dysfunction, the mechanisms of which remain unexplored.

Consulter en ligne

Suggestions

Du même auteur

L-type Ca v 1.3 channels regulate ryanodine receptor-dependent Ca 2+ release during sino-atrial node pacemaker activity

Archive ouverte | Torrente, Angelo | CCSD

International audience. Sino-atrial node (SAN) automaticity is an essential mechanism of heart rate generation that is still not completely understood. Recent studies highlighted the importance of intracellular Ca(2...

RyRCa 2+ Leak Limits Cardiac Ca 2+ Window Current Overcoming the Tonic Effect of Calmodulin in Mice

Archive ouverte | Fernández-Velasco, Maria | CCSD

International audience

Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.. Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.: Ca2+ handling in RyRR4496C mice cardiomyocytes

Archive ouverte | Fernández-Velasco, María | CCSD

International audience. Cardiac ryanodine receptor (RyR2) mutations are associated with autosomal dominant catecholaminergic polymorphic ventricular tachycardia, suggesting that alterations in Ca(2+) handling underl...

Chargement des enrichissements...