Radiotherapy boost in patients with hypoxic lesions identified by 18F-FMISO PET/CT in non-small-cell lung carcinoma: can we expect a better survival outcome without toxicity? [RTEP5 long-term follow-up].

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Vera, Pierre | Mihailescu, Sorina-Dana | Lequesne, Justine | Modzelewski, Romain | Bohn, Pierre | Hapdey, Sébastien | Pepin, Louis-Ferdinand | Dubray, Bernard | Chaumet-Riffaud, Philippe | Decazes, Pierre | Thureau, Sébastien

Edité par CCSD ; Springer Verlag (Germany) [1976-....] -

International audience. Chemoradiotherapy is the reference curative-intent treatment for nonresectable locally advanced non-small-cell lung carcinoma (NSCLC), with unsatisfactory survival, partially due to radiation resistance in hypoxic tissues. The objective was to update survival and toxicity at 3 years following radiotherapy boost to hypoxic tumours in NSCLC patients treated with curative-intent chemoradiotherapy.

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