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Prognostic value of sarcopenia in patients treated by Radiochemotherapy for locally advanced oesophageal cancer

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Mallet, Romain | Modzelewski, Romain | Lequesne, Justine | Mihailescu, Sorina | Decazes, Pierre | Auvray, Hugues | Benyoucef, Ahmed | Di Fiore, Frédéric | Vera, Pierre | Dubray, Bernard | Thureau, Sébastien

Edité par CCSD ; BioMed Central -

International audience. Sarcopenia is defined by a loss of skeletal muscle mass with or without loss of fat mass. Sarcopenia has been associated to reduced tolerance to treatment and worse prognosis in cancer patients, including patients undergoing surgery for limited oesophageal cancer. Concomitant chemo-radiotherapy is the standard treatment for locally-advanced tumour, not accessible to surgical resection. Using automated delineation of the skeletal muscle, we have investigated the prognostic value of sarcopenia in locally advanced oesophageal cancer (LAOC) patients treated by curative-intent chemo-radiotherapy.

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