Suggestions

Du même auteur

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development

Archive ouverte | Siddam, Archana, D | CCSD

International audience. Opacification of the ocular lens, termed cataract, is a common cause of blindness. To become transparent, lens fiber cells undergo degradation of their organelles, including their nuclei, pre...

RNA sequencing analysis of Celf1 mouse mutants identifies a cohort of abnormally expressed lens development regulators

Archive ouverte | Siddam, Archana D. | CCSD

International audience. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA, MAY 01-05, 2016

The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development

Archive ouverte | Aryal, Sandeep | CCSD

International audience. The homeodomain transcription factors (TFs) Pax6 (OMIM 607108) and Prox1 (OMIM 601546) critically regulate gene expression in lens development. While PAX6 mutations in humans can cause catara...

Chargement des enrichissements...