Predictors of palliative treatment in stage IV colorectal cancer

Article

OSAGIEDE, Osayande | SPAULDING, Aaron C. | FRANK, Ryan D. | MERCHEA, Amit | UITTI, Ryan | AILAWADHI, Sikander | KELLEY, Scott | COLIBASEANU, Dorin

BACKGROUND: Palliative treatment may be associated with prolonged survival and improved quality of life, but remains underutilized in stage IV colorectal (CRC). We examined a national cohort of stage IV CRC patients to determine the factors associated with palliative treatment. METHODS: Stage IV CRC patients, classified based on their survival length (<6 months, 6-24 months, and 24 + months), were analyzed using the American College of Surgeons National Cancer Data Base (2004-2013). Multivariable analysis was performed to evaluate factors associated with palliative treatment. RESULTS: Of 85,981 patients analyzed, 10.9% received palliative treatment. For 6-24 months survival, a more recent year of diagnosis, Medicaid, uninsured status, Mountain and Pacific regions were associated with higher odds of palliative treatment. For those who survived < 6months, older patients had lower odds, while academic centers and residence > 20 miles from treating institutions were associated with increased likelihood of palliative treatment. CONCLUSIONS: Palliative treatment in stage IV CRC is associated with a more recent year of diagnosis, Medicaid, academic centers, Mountain and Pacific regions of the US.

http://dx.doi.org/10.1016/j.amjsurg.2018.12.016

Voir la revue «American journal of surgery»

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