Decision-making on withholding or withdrawing life support in the ICU : a worldwide perspective

Article

LOBO, Suzana M. | DE SIMONI, Flávio H. B. | JAKOB, Stephan M. | ESTELLA, Angel | VADI, Sonali | BLUETHGEN, Andreas | MARTIN-LOECHES, Ignacio | SAKR, Yasser | VINCENT, Jean-Louis

Background: Many critically ill patients who die will do so after a decision has been made to withhold/withdraw life-sustaining therapy. The objective of this study was to document the characteristics of ICU patients with a decision to withhold/withdraw life-sustaining treatment, including the types of supportive treatments used, patterns of organ dysfunction, and international differences, including gross national income (GNI). Methods: In this observational cohort study conducted in 730 ICUs in 84 countries, all adult patients admitted between May 8, 2012, and May 18, 2012 (except admissions for routine postoperative surveillance), were included. Results: The analysis included 9,524 patients, with a hospital mortality of 24%. A decision to withhold/withdraw life-sustaining treatment was reported during the ICU stay in 1,259 patients (13%), including 820 (40%) nonsurvivors and 439 (5%) survivors. Hospital mortality in patients with a decision to withhold/withdraw life-sustaining treatment was 69%. The proportion of deaths in patients with a decision to withhold/withdraw life-sustaining treatment ranged from 10% in South Asia to 67% in Oceania. Decisions to withhold/withdraw life-sustaining treatment were less frequent in low/lower-middle GNI countries than in high GNI countries (6% vs 14%; P < .001). Greater disease severity, presence of >= 2 organ failures, severe comorbidities, medical and trauma admissions, and admission from the ED or hospital floor were independent predictors of a decision to withhold/withdraw life-sustaining treatment. Conclusions: There is considerable worldwide variability in decisions to withhold/withdraw life-sustaining treatments. Interestingly, almost one-third of patients with a decision to withhold/withdraw life-sustaining treatment left the hospital alive.

https://www.sciencedirect.com/science/article/pii/S0012369217308206

Voir la revue «Chest, 152»

Autres numéros de la revue «Chest»

Consulter en ligne

Suggestions

Du même auteur

Decision-making on withholding or withdrawing...

Article indépendant | LOBO, Suzana M. | Chest | n°2 | vol.152

Background: Many critically ill patients who die will do so after a decision has been made to withhold/withdraw life-sustaining therapy. The objective of this study was to document the characteristics of ICU patients with a decisi...

Decision-making on withholding or withdrawing...

Article indépendant | LOBO, Suzana M. | Chest | n°2 | vol.152

Background: Many critically ill patients who die will do so after a decision has been made to withhold/withdraw life-sustaining therapy. The objective of this study was to document the characteristics of ICU patients with a decisi...

Variations in end-of-life practices in intens...

Article | AVIDAN, Alexander | The Lancet. Respiratory medicine

Background: End-of-life practices vary among intensive care units (ICUs) worldwide. Differences can result in variable use of disproportionate or non-beneficial life-sustaining interventions across diverse world regions. This stud...

De la même série

Perceptions of life support and advance care ...

Article | PATEL, Vishal R. | Chest | n°6 | vol.161

BACKGROUND: The COVID-19 pandemic has presented new challenges surrounding end-of-life planning and has been associated with increased online discussion about life support. RESEARCH QUESTION: How has online communication about adv...

A medical student perspective on physician-as...

Article | RHEE, John Y. | Chest | n°3 | vol.152

Physician assisted suicide and euthanasia (PAS/E) has been increasingly discussed and debated in the public square, including in professional medical organizations. However, the medical student perspective on the debate has been e...

Decision-making on withholding or withdrawing...

Article | LOBO, Suzana M. | Chest | n°2 | vol.152

Background: Many critically ill patients who die will do so after a decision has been made to withhold/withdraw life-sustaining therapy. The objective of this study was to document the characteristics of ICU patients with a decisi...

The Project ENABLE Cornerstone randomized con...

Article indépendant | BECHTHOLD, Avery C. | Trials | n°1 | vol.23

BACKGROUND: Family caregivers play a vital, yet stressful role in managing the healthcare needs and optimizing the quality of life of patients with advanced cancer, from the time they are newly diagnosed until end of life. While e...

Effectiveness of a complex regional advance c...

Article indépendant | GÖTZE, Kornelia | Trials | n°1 | vol.23

Background: According to recent legislation, facilitated advance care planning (ACP) for nursing home (NH) residents is covered by German sickness funds. However, the effects of ACP on patient-relevant outcomes have not been studi...

Chargement des enrichissements...