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Identification and characterization of auxiliary proteins encoded by the STLV-3 retrovirus pX region

Archive ouverte | Turpin, Jocelyn | CCSD

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HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).

Archive ouverte | Kuhlmann, Anne-Sophie | CCSD

BACKGROUND: Activation of telomerase is a critical and late event in tumor progression. Thus, in patients with adult-T cell leukaemia (ATL), an HTLV-1 (Human T cell Leukaemia virus type 1)-associated disease, leukemic cells displa...

Human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein induces DNA damages through Activation-Induced cytidine Deaminase (AID)

Archive ouverte | Riquet, Aurélien | CCSD

International audience. How T cells are transformed by HTLV-1 is still unclear, but it is well accepted that the viral oncoprotein Tax is associated with genomic instability of infected cells. Tax has recently been ...

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