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Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses

Archive ouverte | Turpin, Jocelyn | CCSD

International audience. Human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 encode auxiliary proteins that play important roles in viral replication, viral latency, and immune escape. The presence of auxiliar...

HTLV-1 propels thymic human T cell development in "human immune system" Rag2-/- IL-2R γc-/- Mice

Archive ouverte | Villaudy, Julien | CCSD

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HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).

Archive ouverte | Kuhlmann, Anne-Sophie | CCSD

BACKGROUND: Activation of telomerase is a critical and late event in tumor progression. Thus, in patients with adult-T cell leukaemia (ATL), an HTLV-1 (Human T cell Leukaemia virus type 1)-associated disease, leukemic cells displa...

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