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Altered b lymphocyte homeostasis and functions in systemic sclerosis

Archive ouverte | Forestier, Alexandra | CCSD

International audience. Beyond the production of autoantibodies, B-cells are thought to play a role in systemic sclerosis (SSc) by secreting proinflammatory/profibrotic cytokines. B-cells are a heterogeneous populat...

B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis

Archive ouverte | Sanges, Sébastien | CCSD

International audience. During systemic sclerosis (SSc), peripheral B cells display alterations in subset homeostasis and functional properties and are a promising therapeutic target. However, there is only few data...

Effect of In Vitro and In Vivo Anakinra on Cytokines Production in Schnitzler Syndrome

Archive ouverte | Launay, David | CCSD

International audience. IL-1 receptor antagonist anakinra is usually highly efficient in Schnitzler syndrome (SS), a rare inflammatory condition associating urticaria, fever, and IgM monoclonal gammopathy. In this s...

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