B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis

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Sanges, Sébastien | Jendoubi, Manel | Kavian, Niloufar | Hauspie, Carine | Speca, Silvia | Crave, Jean-Charles | Guerrier, Thomas | Lefèvre, Guillaume | Sobanski, Vincent | Savina, Ariel | Hachulla, Eric | Hatron, Pierre-Yves | Labalette, Myriam | Batteux, Frédéric | Dubucquoi, Sylvain | Launay, David

Edité par CCSD ; Frontiers -

International audience. During systemic sclerosis (SSc), peripheral B cells display alterations in subset homeostasis and functional properties and are a promising therapeutic target. However, there is only few data regarding whether these anomalies are accurately reproduced in animal models of SSc.

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