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Archive ouverte | Le Voyer, Tom | CCSD

Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)1,2, conferring a predisposition to life-threatening...

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Archive ouverte | Le Voyer, Tom | CCSD

International audience. Abstract Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs) 1,2...

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