Composition comprising a lasso peptide formulated in a pharmaceuticallyacceptable nanoemulsion

Archive ouverte

Giraud, Caroline | Li, Yanyan | Goulard, Christophe | Hartke, Axel | Boudrioua, Abdelhakim | Baëtz, Benjamin

Edité par CCSD -

The present invention relates to a composition comprising a lasso peptide formulated in a pharmaceutically acceptable nanoemulsion and an antibiotic, to said composition for use as a medicine, and to a method for producing said composition. The composition of the present invention finds an application for example for thetreatment of an infection by a Gram-positive bacterium.

Consulter en ligne

Suggestions

Du même auteur

Lasso peptides sviceucin and siamycin I have anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant Enterococcus sp. and Staphylococcus aureus

Archive ouverte | Boudrioua, Abdelhakim | CCSD

Antibiotic resistance is a major threat to human health and new drugs are urgently needed. Ideally, these drugs should have several cellular targets in pathogens, decreasing the risk of resistance development. We show here that tw...

Lasso peptides sviceucin and siamycin I exhibit anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant pathogens

Archive ouverte | Boudrioua, Abdelhakim | CCSD

International audience. Antibiotic resistance is a major threat to human health and new drugs are urgently needed. Ideally, these drugs should have several cellular targets in pathogens, decreasing the risk of resis...

Peptides lasso actifs contre des pathogènes à Gram positif d’intérêts cliniques

Archive ouverte | Giraud, Caroline | CCSD

International audience

Chargement des enrichissements...