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Lasso peptides sviceucin and siamycin I have anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant Enterococcus sp. and Staphylococcus aureus

Archive ouverte | Boudrioua, Abdelhakim | CCSD

Antibiotic resistance is a major threat to human health and new drugs are urgently needed. Ideally, these drugs should have several cellular targets in pathogens, decreasing the risk of resistance development. We show here that tw...

Study of anti-resistance and anti-virulence effects of two antimicrobialmolecules on Gram positive pathogens

Archive ouverte | Baëtz, Benjamin | CCSD

International audience. Introduction et objectifsLes Entérocoques et Staphylocoques sont responsables de nombreuses infections associées aux soins. Ces organismes présentent des résistances à divers antibiotiques do...

Study of anti-resistance and anti-virulence effects of two antimicrobial molecules on Gram positive pathogens

Archive ouverte | Baëtz, Benjamin | CCSD

International audience. Enterococci and Staphylococci are responsible for many healthcare associated infections. These microorganisms harbor different antibiotic resistances, including vancomycin. These Enterococci ...

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