Consistency of Mycobacterium tuberculosis Complex Spoligotyping between the Membrane-Based Method and In Silico Approach

0 avis

Consistency of Mycobacterium tuberculosis Complex Spoligotyping between the Membrane-Based Method and In Silico Approach

Archive ouverte

Edité par CCSD ; American Society for Microbiology -

International audience. Whole-genome sequencing (WGS) has profoundly transformed the perspectives of tuberculosis (TB) diagnosis, providing a better discriminatory power to determine relatedness between Mycobacterium tuberculosis complex (MTBC) isolates. Previous genotyping approaches, such as spoligotyping consisting of an initial PCR step followed by reverse dot hybridization, are currently being replaced by WGS.

Langue: en

Consulter en ligne

Consulter le document

Suggestions

Du même auteur

Rapid resistance detection is reliable for prompt adaptation of isoniazid resistant tuberculosis management

Archive ouverte | Bahuaud, Olivier | CCSD

International audience. Objectives: Appropriate tuberculosis (TB) management requires anti-TB drugs resistance detection. We assessed the performance of rapid resistance detection assays and their impact on treatmen...

Mycobacterium tuberculosis genetic features associated with pulmonary tuberculosis severity

Archive ouverte | Genestet, Charlotte | CCSD

International audience. Objective: Mycobacterium tuberculosis (Mtb) infections result in a wide spectrum of clinical presentations but without proven Mtb genetic determinants. Herein, we hypothesised that genetic fe...

Within-host genetic micro-diversity of Mycobacterium tuberculosis and the link with tuberculosis disease features

Archive ouverte | Genestet, Charlotte | CCSD

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) complex, is still the number one deadly contagious disease. Mtb infection results in a wide spectrum of clinical presentations and severity symptoms, but without proven...

Chargement des enrichissements...