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Non-Polio Enterovirus inhibitors : scaffolds, targets, and potency - what's new ?

Archive ouverte | Roux, H.F.G. | CCSD

Enterovirus (EV) is a genus that includes a large diversity of viruses spread around the world. They are the main cause of numerous diseases with seasonal clusters, like hand-foot-mouth disease (HFMD). A vaccine is marketed in Chi...

New potent EV-A71 antivirals targeting capsid

Archive ouverte | Roux, Hugo | CCSD

International audience. The enterovirus is a genus of single-stranded, highly diverse positive-sense RNA viruses, including Human Enterovirus A-D and Human Rhinovirus A-C species. They are responsible for numerous d...

Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential

Archive ouverte | Khoumeri, Omar | CCSD

International audience. A series of 61 thiazolidine-2,4-diones bearing a styryl group at position 5 was synthesized in 2–5 steps and their structure was proved by elemental and spectral analyses. The compounds obtai...

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