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A catalog of numerical centrosome defects in epithelial ovarian cancers

Archive ouverte | Morretton, Jean‐philippe | CCSD

International audience. Centrosome amplification, the presence of more than two centrosomes in a cell is a common feature of most human cancer celllines. However, little is known about centrosome numbers inhuman can...

Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions

Archive ouverte | Edwards, Frances | CCSD

International audience. ABSTRACT Centrosome amplification is a feature of cancer cells associated with chromosome instability and invasiveness. Enhancing chromosome instability and subsequent cancer cell death via c...

Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy

Archive ouverte | Edwards, Frances | CCSD

International audience. Centrosome amplification is a feature of cancer cells associated with chromosome instability and invasiveness. Enhancing chromosome instability and subsequent cancer cell death via centrosome...

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