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Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis.

Archive ouverte | Nominé, Yves | CCSD

Oncoprotein E6 is essential for oncogenesis induced by human papillomaviruses (HPVs). The solution structure of HPV16-E6 C-terminal domain reveals a zinc binding fold. A model of full-length E6 is proposed and analyzed in the cont...

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Archive ouverte | Nominé, Yves | CCSD

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Archive ouverte | Fournane, Sadek | CCSD

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