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Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells

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Bourdely, Pierre | Anselmi, Giorgio | Vaivode, Kristine | Ramos, Rodrigo, Nalio | Missolo-Koussou, Yoann | Hidalgo, Sofia | Tosselo, Jimena | Nuñez, Nicolas | Richer, Wilfrid | Vincent-Salomon, Anne | Saxena, Alka | Wood, Kristie | Lladser, Alvaro | Piaggio, Eliane | Helft, Julie | Guermonprez, Pierre

Edité par CCSD ; Elsevier -

International audience. Highlights d DC3s are phenotypic and functional intermediates between cDC2s and monocytes d GM-CSF alone, but not FLT3L, supports efficient differentiation of DC3s d DC3s do not differentiate via cDC (CDP)-or monocyterestricted (cMoP) progenitors d DC3s prime T RM cells in vitro and correlate with T RM expansion in primary breast cancer

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