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Mechanism of Naphthoquinone Selectivity of Thymidylate Synthase ThyX

Archive ouverte | Myllykallio, Hannu | CCSD

International audience. Naphthoquinones (NQs) are natural and synthetic compounds with a wide range of biological activities commonly attributed to their redox activity and/or chemical reactivity. However, genetic a...

Bacterial origin of thymidylate and folate metabolism in Asgard Archaea

Archive ouverte | Filée, Jonathan | CCSD

Abstract Little is known about the evolution and biosynthetic function of DNA precursor and the folate metabolism in the Asgard group of archaea. As Asgard occupy a key position in the archaeal and eukaryotic phylogenetic trees, w...

High-Throughput Sequencing Reveals Circular Substrates for an Archaeal RNA ligase.

Archive ouverte | Becker, Hubert F | CCSD

International audience

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