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N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease

Archive ouverte | Jörg, Marko | CCSD

International audience. Abstract One mechanism of particular interest to regulate mRNA fate post-transcriptionally is mRNA modification. Especially the extent of m 1 A mRNA methylation is highly discussed due to met...

Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures

Archive ouverte | Schmidt, Lukas | CCSD

International audience

A Vastly Increased Chemical Variety of RNA Modifications Containing a Thioacetal Structure

Archive ouverte | Dal Magro, Christina | CCSD

International audience. Recently discovered new chemical entities in RNA modifications have involved surprising functional groups that enlarge the chemical space of RNA. Using LC-MS, we found over 100 signals of RNA...

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