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SigmaR1 regulates membrane electrical activity in response to extracellular matrix stimulation to drive cancer cell invasiveness.

Archive ouverte | Crottès, David | CCSD

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Archive ouverte | Crottes, David | CCSD

International audience. Sigma-1 receptor (Sig1R) is a 25-kDa protein structurally unrelated to other mammalian proteins. Sig1R is present in brain, liver, and heart and is overexpressed in cancer cells. Studies usin...

Sigma 1 receptor regulates HERG channel expression through a post-translational mechanism in leukemic cells.

Archive ouverte | Crottes, David | CCSD

International audience. Sigma-1 receptor (Sig1R) is a 25-kDa protein structurally unrelated to other mammalian proteins. Sig1R is present in brain, liver, and heart and is overexpressed in cancer cells. Studies usin...

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