Suggestions

Du même auteur

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

Archive ouverte | Contrepois, Kévin | CCSD

International audience. The senescence of mammalian cells is characterized by a proliferative arrest in response to stress and the expression of an inflammatory phenotype. Here we show that histone H2A.J, a poorly s...

Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1. Conception sur une base rationnelle de peptides de haute affinité inhibant l'histone chaperon ASF1

Archive ouverte | Bakail, May | CCSD

International audience. Anti-silencing function 1 (ASF1) is a conserved H3-H4 histone chaperone involved in histone dynamics during replication, transcription, and DNA repair. Overexpressed in proliferating tissues ...

Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

Archive ouverte | Contrepois, Kévin | CCSD

International audience. Cellular senescence is a stress response of mammalian cells leading to a durable arrest of cell proliferation that has been implicated in tumor suppression, wound healing, and aging. The prol...

Chargement des enrichissements...