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HLAIb worldwide genetic diversity: new HLA-H alleles and haplotype structure description

Archive ouverte | Paganini, Julien | CCSD

International audience. The classical HLA class I genes (HLA Ia) were extensively studied because of their implication in clinical fields and anthropology. Less is known about worldwide genetic diversity and linkage...

Identification of eleven novel HLA‐A , ‐B, ‐C, ‐ DRB1 and ‐ DQB1 alleles in the 1000 Genomes Project panel

Archive ouverte | Di Cristofaro, Julie | CCSD

International audience. We isolated 11 novel HLA alleles in the 1,000 Genomes Project using PolyPheMe software. This article is protected by copyright. All rights reserved.

Immune diversity sheds light on missing variation in worldwide genetic diversity panels

Archive ouverte | Abi-Rached, Laurent | CCSD

International audience. Defining worldwide human genetic variation is a critical step to reveal how genome plasticity contributes to disease. Yet, there is currently no metric to assess the representativeness and co...

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