Transmitted drug resistance in French HIV-2-infected patients.

Archive ouverte

Charpentier, Charlotte | Visseaux, Benoit | Bénard, Antoine | Peytavin, Gilles | Damond, Florence | Roy, Céline | Taieb, Audrey | Chêne, Geneviève | Matheron, Sophie | Brun-Vézinet, Francoise | Descamps, Diane | Michelet, Christian

Edité par CCSD ; Wolters Kluwer -

International audience. We report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in protease, not in reverse transcriptase. In this series, 10% of patients displayed X4/dual-mixed viruses. These findings classified the rate of transmitted drug resistance in the HIV-2 French Cohort as low prevalence.

Consulter en ligne

Suggestions

Du même auteur

In Vitro Phenotypic Susceptibility of Human Immunodeficiency Virus Type 2 Clinical Isolates to Protease Inhibitors.

Archive ouverte | Desbois, Delphine | CCSD

International audience. We determine phenotypic susceptibility of human immunodeficiency virus type 2 (HIV-2) isolates to amprenavir, atazanavir, darunavir, indinavir, lopinavir, nelfinavir, saquinavir, and tipranav...

Salvage Therapy Including Foscarnet and Ibalizumab for Multidrug-Resistant Human Immunodeficiency Virus Type 2 Infection

Archive ouverte | Bachelard, Antoine | CCSD

International audience. Abstract We evaluated Ibalizumab (IBA)-containing standardized optimized salvage regimen (with or without a 4-week foscarnet induction) in individuals harboring multidrug-resistant human immu...

Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates

Archive ouverte | Visseaux, Benoit | CCSD

International audience. Background: Maraviroc activity against HIV-2, a virus naturally resistant to different HIV-1 antiretroviral drugs, has been recently demonstrated. The aim of this study was to assess HIV-2 su...

Chargement des enrichissements...