The PGD2 pathway, independently of FGF9, amplifies SOX9activity in Sertoli cells during male sexual differentiation

Archive ouverte | Moniot, B. | CCSD

International audience. Activation by the Y-encoded testis determining factor SRY and maintenance of expression of the Sox9 gene encoding the central transcription factor of Sertoli cell differentiation are key even...

La Prostaglandine D2: nouveaux rôles dans la gonade embryonnaire et pathologique

Archive ouverte | Malki, S. | CCSD

Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis

Archive ouverte | Moniot, B. | CCSD

International audience. Through intercellular signalling, the somatic compartment of the foetal testis is able to program primordial germ cells to undergo spermatogenesis.Fibroblastgrowthfactor9 and several members ...