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The PGD2 pathway, independently of FGF9, amplifies SOX9activity in Sertoli cells during male sexual differentiation

Archive ouverte | Moniot, B. | CCSD

International audience. Activation by the Y-encoded testis determining factor SRY and maintenance of expression of the Sox9 gene encoding the central transcription factor of Sertoli cell differentiation are key even...

Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein

Archive ouverte | Moniot, B. | CCSD

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Archive ouverte | Moniot, B. | CCSD

International audience. Through intercellular signalling, the somatic compartment of the foetal testis is able to program primordial germ cells to undergo spermatogenesis.Fibroblastgrowthfactor9 and several members ...

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