The amygdala encodes specific sensory features of an aversive reinforcer.

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Debiec, Jacek | Diaz-Mataix, Lorenzo | Bush, David E. A. | Doyère, Valérie | Ledoux, Joseph E.

Edité par CCSD ; Nature Publishing Group -

International audience. Studies of reconsolidation, in which retrieved memories are altered and restored, offer an approach for exploring the associative structure of fear memory. We found that exposure to the unconditioned stimulus initiates an unconditioned stimulus-specific reconsolidation of learned fear in rats that depended on the amygdala. Thus, specific features of the unconditioned stimulus appear to be encoded in the amygdala as part of fear memories stored there.

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The selectivity of aversive memory reconsolidation and extinction processes depends on the initial encoding of the Pavlovian association.

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