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Continuous MYD88 activation is associated with expansion and then transformation of IgM differentiating plasma cells

Archive ouverte | Ouk, Catherine | CCSD

International audience

Continuous MYD88 Activation Is Associated With Expansion and Then Transformation of IgM Differentiating Plasma Cells

Archive ouverte | Ouk, Catherine | CCSD

International audience. Activating mutations of MYD88 ( MYD88 L265P being the far most frequent) are found in most cases of Waldenström macroglobulinemia (WM) as well as in various aggressive B-cell lymphoma entitie...

Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories.

Archive ouverte | Parrens, M. | CCSD

International audience

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