Advance directives in the intensive care unit : an eight-year vanguard cohort study

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BAUMANN, Sira M. | AMACHER, Simon A. | ERNE, Yasmin | GRZONKA, Pascale | BERGER, Sebastian | HUNZIKER, Sabina | GEBHARD, Caroline E. | NEBIKER, Mathias | CIOCCARI, Luca | SUTTER, Raoul

PURPOSE: To investigate the frequency, content, and clinical translation of advance directives in intensive care units (ICUs). MATERIAL AND METHODS: Retrospective cohort study in a Swiss tertiary ICU, including patients with advance directives treated in ICUs = 48 h. The primary endpoint was the violation of directives. Key secondary endpoints were the directives' prevalence and their translation into clinical practice. RESULTS: Of 5'851 patients treated = 48 h in ICUs, 2.7 % had documented directives. Despite 92 % using templates, subjective or contradictory wording was found in 19 % and 12 %. Nine percent of directives were violated. Patients with directive violations had worse in-hospital outcomes (p = 0.012). At admission, 64 % of patients experiencing violations could not communicate, and directives were missing/unrecognized in 30 %. Mostly, directives were not followed regarding life-prolonging measures (6 %), ICU admission (5 %), and mechanical ventilation (3 %). Kaplan Meier statistics revealed a lower survival rate with directives recognized at admission (p = 0.04) and when treatment was withheld (p < 0.001). CONCLUSIONS: Advance directives are available in a minority of ICU patients and often contain subjective/contradictory wording. Physicians respected directives in 90 % of patients, with treatment adapted following their wishes. However, violation of directives may have serious consequences with unfavorable in-hospital outcomes and decreased long-term survival with treatment adaption following directives.

http://dx.doi.org/10.1016/j.jcrc.2024.154918

Voir la revue «Journal of critical care, 85»

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