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Characterization of the promoter of the human KAL gene, responsible for the X-chromosome-linked Kallmann syndrome

Archive ouverte | Cohen-Salmon, Martine | CCSD

International audience. We report on the first characterization of the human KAL promoter (pKAL), based on the analysis of a 2-kb fragment of the 5′ flanking region. As determined by primer extension, transcription ...

Structure of the X–linked Kallmann syndrome gene and its homologous pseudogene on the Y chromosome

Archive ouverte | Castillo, Ignacio Del | CCSD

International audience. The gene for the X-linked Kallmann syndrome (KAL), a developmental disorder characterized by hypogonadotropic hypogonadism and anosmia, maps to Xp22.3 and has a homologous locus, KALP, on Yq1...

Characterization of the Chicken and Quail Homologues of the Human Gene Responsible for the X-Linked Kallmann Syndrome

Archive ouverte | Legouis, Renaud | CCSD

International audience. The human KAL gene, responsible for the X-linked Kallmann syndrome, was isolated previously. Southern blot analysis using human cDNA probes detected cross-hybridization with DNA from several ...

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