Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
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Rosain, Jérémie | Neehus, Anna-Lena | Manry, Jérémy | Yang, Rui | Le Pen, Jérémie | Daher, Wassim | Liu, Zhiyong | Chan, Yi-Hao | Tahuil, Natalia | Türel, Özden | Bourgey, Mathieu | Ogishi, Masato | Doisne, Jean-Marc | Izquierdo, Helena, M | Shirasaki, Takayoshi | Le Voyer, Tom | Guérin, Antoine | Bastard, Paul | Moncada-Vélez, Marcela | Han, Ji, Eun | Khan, Taushif | Rapaport, Franck | Hong, Seon-Hui | Cheung, Andrew | Haake, Kathrin | Mindt, Barbara, C | Pérez, Laura | Philippot, Quentin | Lee, Danyel | Zhang, Peng | Rinchai, Darawan | Al Ali, Fatima | Ahmad Ata, Manar, Mahmoud | Rahman, Mahbuba | Peel, Jessica, N | Heissel, Søren | Molina, Henrik | Kendir-Demirkol, Yasemin | Bailey, Rasheed | Zhao, Shuxiang | Bohlen, Jonathan | Mancini, Mathieu | Seeleuthner, Yoann | Roelens, Marie | Lorenzo, Lazaro | Soudée, Camille | Paz, María, Elvira Josefina | González, María, Laura | Jeljeli, Mohamed | Soulier, Jean | Romana, Serge | L’honneur, Anne-Sophie | Materna, Marie | Martínez-Barricarte, Rubén | Pochon, Mathieu | Oleaga-Quintas, Carmen | Michev, Alexandre | Migaud, Mélanie | Lévy, Romain | Alyanakian, Marie-Alexandra | Rozenberg, Flore | Croft, Carys, A | Vogt, Guillaume | Emile, Jean-François | Kremer, Laurent | Ma, Cindy, S | Fritz, Jörg, H | Lemon, Stanley, M | Spaan, András, N | Manel, Nicolas | Abel, Laurent | Macdonald, Margaret, R | Boisson-Dupuis, Stéphanie | Marr, Nico | Tangye, Stuart, G | Di Santo, James, P | Zhang, Qian | Zhang, Shen-Ying | Rice, Charles, M | Béziat, Vivien | Lachmann, Nico | Langlais, David | Casanova, Jean-Laurent | Gros, Philippe | Bustamante, Jacinta
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CCSD ; Elsevier -
International audience.
Highlights d Inherited complete human IRF1 deficiency underlies severe mycobacterial disease d Human IRF1 is essential for IFN-g-dependent macrophagic immunity to mycobacteria d Human IRF1 is essential for IFN-g-and STAT1-dependent immunity to mycobacteria d Human IRF1 is largely redundant for IFN-a/b-dependent antiviral intrinsic immunity Authors Je ´re ´mie Rosain,
