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A race between SARS-CoV-2 variants and vaccination: The case of the B.1.1.7 variant in France

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Bosetti, Paolo | Tran Kiem, Cécile | Andronico, Alessio | Paireau, Juliette | Levy Bruhl, Daniel | Lina, Bruno | Yazdanpanah, Yazdan | Fontanet, Arnaud | Colizza, Vittoria | Boëlle, Pierre-Yves | Cauchemez, Simon

Edité par CCSD -

The SARS-CoV-2 pandemic has entered an uncertain race between the emergence of variants that are more transmissible and vaccine roll-out. Here, we developed a mathematical model to evaluate how the interplay of variants, vaccines and non-pharmaceutical interventions might shape the pandemic dynamics, using the rise of the B.1.1.7 variant in metropolitan France as a case study. Our analysis highlights the challenges ahead for the management of the SARS-CoV-2 pandemic and shows how the quick roll-out of vaccines to at-risk individuals and non-pharmaceutical interventions are needed to mitigate the impact of the emerging variants.

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