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A Reliable Diagnosis of Human Rabies Based on Analysis of Skin Biopsy Specimens

Archive ouverte | Dacheux, Laurent | CCSD

International audience. BACKGROUND:The number of human deaths due to rabies is currently underestimated to be 55,000 deaths per year. Biological diagnostic methods for confirmation of rabies remain limited, because ...

Role of interferons in the control of Lassa virus replication in human dendritic cells and macrophages

Archive ouverte | Baize, Sylvain | CCSD

International audience. Lassa fever is a hemorrhagic fever caused by Lassa virus (LV), which primarily targets human dendritic cells (DC) and macrophages (MP). Massive numbers of viral particles are released with no...

Lassa Virus Infection of Human Dendritic Cells and Macrophages Is Productive but Fails to Activate Cells

Archive ouverte | Baize, Sylvain | CCSD

International audience. Lassa fever is a hemorrhagic fever caused by Lassa virus (LV), an old-world Arenavirus. Little is known about the immune responses that occur during the disease, but protection seems to be li...

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