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Experimental infection of squirrel monkeys with nipah virus.

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Marianneau, Philippe | Guillaume, Vanessa | Wong, Thong | Badmanathan, Munisamy | Looi, Ren Yih | Murri, Severine | Loth, Philippe | Tordo, Noel | Wild, Fabian, T. | Horvat, Branka | Contamin, Hugues

Edité par CCSD ; Centers for Disease Control and Prevention -

International audience. We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.

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