Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy

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Landre, S. | Bienvenu, A. L. | Miailhes, P. | Abraham, P. | Simon, M. | Becker, A. | Conrad, A. | Bonnot, G. | Kouakou, Y. I. | Chidiac, C. | Leboucher, G. | Rimmele, T. | Argaud, L. | Picot, S.

Edité par CCSD ; Elsevier -

International audience. A patient presenting with severe malaria, with hyperparasitaemia, received 7-day artesunate monotherapy. A severe recrudescence was detected and attributed to hyperparasitaemia, monotherapy and a polyclonal infection without Kelch 13 gene mutation. A second treatment with artesunate, then quinine, followed by artemether-lumefantrine, was successful.

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